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Chondroitin sulfate and glucosamine in the cartilage and subchondral bone repair of dogs - Histological findings Arq. Bras. Med. Vet. Zootec.
Eleotério,R.B.; Pontes,K.C.S.; Machado,J.P.; Reis,E.C.C.; Ferreira,P.S.; Silva,M.B.; Martins,N.J.S.; Fernandes,N.A.; Borges,A.P.B..
Chondroitin and glucosamine sulfate nutraceuticals are commonly used in the management of degenerative articular disease in veterinary routine. However, there are controversies on the contribution of these substances to articular cartilage. The purpose of this study was to evaluate the efficiency of a chondroitin and glucosamine sulfate-based veterinary nutraceutical on the repair of an induced osteochondral defect in a dog femoral condyle, by macroscopic, histological and histomorphometric analyses. The nutraceutical was orally administered the day following injury induction, every 24 hours (treated group, TG, n=24), compared with animals that did not receive the product (control group, CG, n=24). Six animals per group were anaesthetized for sample...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Degenerative articular disease; Osteoarthritis; Arthrosis; Chondroprotective; Cartilage.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000200325
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Development and evaluation of a novel subunit vaccine for Mycoplasma gallisepticum Arq. Bras. Med. Vet. Zootec.
Moura,L.; Dohms,J.; Almeida,J.M.; Ferreira,P.S.; Biffi,C.P.; Backes,R.G..
Adhesion proteins from Mycoplasma gallisepticum (MG) encoded by cytadhesion genes mgc1 and mgc2 were cloned into plasmid vectors and transformed into E. coli. Seventeen groups of specific-pathogen free (SPF), birds at four weeks of age were used to inoculate these two proteins (MGC1 and MGC2) mixed into an oil emulsion creating a novel MG vaccine. Six different protein concentrations (50, 100, 200, 400, 800, and 1000µg/bird) were tested with two equal concentration doses at four and seven weeks of age. In addition, many control groups were needed such as bacterin, membrane, no vaccine or challenge, oil emulsion alone, and no vaccine but challenged. Three weeks following the second vaccination, 50% of the birds in each treatment group were challenged with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Evaluation; Development; Mycoplasmas; Poultry; Vaccine.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600024
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